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An Interview with Dr. James Crapo, Medical Professor and Member of the EPA's Clean Air Scientific Advisory Committee

Dr. James Crapo is a member of the Clean Air Scientific Advisory Committee, an advisory board to the Administrator of the U.S. Environmental Protection Agency (EPA). He works at National Jewish Medical and Research Center in Denver and as a member of the Committee, reviews National Ambient Air Quality Standards and makes recommendations as to whether they should be revised.

What are National Ambient Air Quality Standards? They are air quality thresholds that protect human health everywhere in this country. They cannot be exceeded anywhere, and state and federal rules must be written to keep air quality from violating these standards. They are one of our most important safeguards under the Clean Air Act. National Ambient Air Quality Standards are established for six pollutants—carbon monoxide, lead, nitrogen oxides, ozone, particulates, and sulfur dioxide. Every five years, criteria documents for ambient air quality standards are reviewed. Criteria documents are like user’s guides to ambient air quality standards. They are an overview of all relevant science and form the basis of recommendations to revise ambient air quality standards.

The Clean Air Scientific Advisory Committee (CASAC) and its work have been in the news a lot lately. The EPA recently adopted particulate air standards that drew fire from the Committee. The Committee also recently recommended that standards for ozone, also known as smog, be strengthened and is in the process of reviewing standards for lead in our air.

Dr. Crapo graciously set aside time in October to do an interview with Rocky Mountain Clean Air Action to discuss the Clean Air Scientific Advisory Committee, his work, and the role of the public.  Our interview follows.

RMCAA:  How did you get on the Committee?

The EPA contacted me two to three years ago and asked if I was willing to be considered for a nomination to the CASAC. From there the nomination went through a review by the agency and led to the final appointment by the EPA administrator. It took around 3-4 months from the day I was invited to day I was appointed.

RMCAA:  What is your time investment?

Overall, I’d say several hundred hours are put into reviewing criteria documents for six criteria pollutants every five years, which is the timeline required by law. The process also includes several meetings that may last up to three days, along with several teleconference calls. We just finished with particulates and now ozone and lead are on the table.

The material we are asked to review for each of the criteria pollutants is enormous. We review scientific literature with a focus of new literature dating from the last time that criteria pollutant was reviewed. We primarily focus on studies of low level exposures that are relevant to current ambient air exposure in this country and determine if there is evidence of an adverse health effect and the severity of those effects. We then assess whether changes to ambient air quality standards are needed in order to adequately protect human health.

RMCAA:  How many people are on the Committee?

There are seven standing members. But for each criteria pollutant review, an ad hoc committee is created by inviting 10-20 additional scientists to join in the review.

RMCAA:  What backgrounds do Committee members represent?

Members come from broad backgrounds, including chemistry, medicine, epidemiology, and work with flora and fauna. They represent the broad range of expertise needed to understand and discuss each of these topics when reviewing air quality criteria and making recommendations.

RMCAA:  How would you describe your background?

I’m a physician. I specialize in pulmonary medicine, and my experience is in lung structure and function and in inhalation toxicology. I’ve done research on the mechanisms of lung injury, including studies of airborne pollutants that enter lungs.

RMCAA:  How long have you been in medicine?

I got my Medical Degree from the University of Rochester in 1971. I started doing research in 1972 and have been doing it ever since, so almost 35 years now.

RMCAA:  What is your work like today?

My focus is on oxidant stress to lungs. We’re attempting to develop new potent antioxidant drugs to treat diseases involving oxidant stress. My primary research focus is on chronic obstructive pulmonary disease (COPD). We’re also trying to understand the genetic basis for COPD so that we can use this information to guide the development of new approaches to therapy.

COPD is otherwise known as emphysema. It’s primarily caused by smoking and is a chronic disease where the lung is destroyed. It’s associated with chronic cough, shortness of breath, and hypoxemia.

RMCAA:  Do criteria pollutants cause or contribute to emphysema?

They can exacerbate lung problems, such as asthma, which has a close tie to air pollution. It is likely that pollutants lead to exacerbation of COPD. With comprised lungs, these pollutants can cause inflammation as a result of irritation of the delicate airways in the lung – and they can help initiate lung infections.

RMCAA:  Can you describe the function of the Clean Air Scientific Advisory Committee?

The Committee is described as an advisory body. It was set up by the Clean Air Act to advise the Administrator of the EPA as to whether or not current air quality standards are protective of human health and welfare.

RMCAA:  As an advisory committee, how much weight should CASAC advice receive?

The advice of Committee should be the primary advice considered when setting ambient air quality standards.

RMCAA:  What role does public input play in your work on the CASAC?

Public comments are a very important part of our review of criteria documents and the setting of ambient air quality standards. We don’t enter into a debate with the public, but take input from the public that will be considered by the Committee. There is lots of helpful input from the public on all sides of each issue.

RMCAA:  What happens once you’ve reviewed one of the criteria pollutants?

At the end of our review, we send a letter to Administrator setting forth our recommendations. The EPA staff then make recommendations regarding any change in the National Air Quality Standard for that criteria pollutant. CASAC then reviews and comments on those staff recommendations, and many provide additional recommendations to the EPA Administrator. After that, the ball is in the court of the EPA Administrator, who issues the final standard.

RMCAA:  How important are National Ambient Air Quality Standards?

Well, they’re the law of the land. Ambient air quality standards are incredibly important; they are the foundation of the Clean Air Act. The Clean Air Act gives EPA the power to enforce standards and set limits through regulations to protect those standards. I think it’s a very appropriate approach that has resulted in a substantial number of actions over the last decade that have led to cleaner air for our country.

RMCAA:  Do you see a parallel path between the strengthening of air quality standards and our level of knowledge on health impacts?

Our knowledge of adverse health effects continues to improve and as such, the standards often get tighter and our air quality improves. We’re not done finding the right air quality standard nor with bringing every part of the country into conformance with those standards. We still have a lot of work to do, and science continues to guide our understanding and our actions.